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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
23.94
Human Site:
Y45
Identified Species:
35.11
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y45
E
S
E
N
G
Q
M
Y
I
Q
K
K
P
T
M
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y45
E
S
E
N
G
Q
M
Y
I
Q
K
K
P
T
M
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
L508
H
P
Q
R
G
K
T
L
V
Q
K
K
P
T
M
Dog
Lupus familis
XP_849292
706
81555
Y45
E
S
E
N
G
Q
M
Y
I
Q
K
K
P
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y45
E
S
E
N
G
Q
M
Y
I
Q
K
K
P
T
M
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y45
E
S
E
N
G
Q
M
Y
I
Q
K
K
P
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y45
E
S
E
N
G
Q
V
Y
V
Q
K
K
P
T
M
Chicken
Gallus gallus
NP_001006133
699
80179
I45
T
E
R
G
K
T
L
I
Q
R
K
P
T
M
Y
Frog
Xenopus laevis
Q7LZQ8
671
76506
C47
F
F
K
Q
P
T
F
C
S
H
C
T
D
F
I
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
F55
F
C
S
H
C
T
D
F
I
W
G
F
G
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K47
E
H
T
V
A
V
N
K
E
F
K
E
R
A
G
Honey Bee
Apis mellifera
XP_394743
624
71014
L47
Y
R
T
R
I
P
I
L
N
P
T
D
L
P
P
Nematode Worm
Caenorhab. elegans
P34722
704
80280
L49
E
V
N
G
E
S
R
L
V
Q
K
K
K
T
L
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
S45
G
G
G
D
P
M
N
S
V
R
S
T
V
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
N181
L
K
K
Y
Q
A
I
N
V
D
F
D
Q
F
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
F54
G
R
R
N
L
E
F
F
E
E
K
L
R
E
L
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
46.6
100
N.A.
100
100
N.A.
86.6
6.6
0
6.6
N.A.
13.3
0
33.3
0
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
100
20
13.3
20
N.A.
20
6.6
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
7
0
0
7
0
0
7
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
7
0
0
7
0
13
7
0
0
% D
% Glu:
50
7
38
0
7
7
0
0
13
7
0
7
0
7
0
% E
% Phe:
13
7
0
0
0
0
13
13
0
7
7
7
0
13
0
% F
% Gly:
13
7
7
13
44
0
0
0
0
0
7
0
7
0
7
% G
% His:
7
7
0
7
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
0
0
0
0
7
0
13
7
38
0
0
0
0
0
7
% I
% Lys:
0
7
13
0
7
7
0
7
0
0
69
50
7
7
7
% K
% Leu:
7
0
0
0
7
0
7
19
0
0
0
7
7
0
13
% L
% Met:
0
0
0
0
0
7
32
0
0
0
0
0
0
7
44
% M
% Asn:
0
0
7
44
0
0
13
7
7
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
13
7
0
0
0
7
0
7
44
7
7
% P
% Gln:
0
0
7
7
7
38
0
0
7
50
0
0
7
0
7
% Q
% Arg:
0
13
13
13
0
0
7
0
0
13
0
0
13
0
0
% R
% Ser:
0
38
7
0
0
7
0
7
7
0
7
0
0
7
0
% S
% Thr:
7
0
13
0
0
19
7
0
0
0
7
13
7
50
0
% T
% Val:
0
7
0
7
0
7
7
0
32
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
38
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _